4SC (VSC)

Business description

4SC is a Munich-based cancer biopharmaceutical company. Resminostat (HDAC inhibitor) is the lead candidate for cutaneous T-Cell lymphoma (pivotal study started in Q416). It has a second compound, 4SC-202 (Phase II) and a preclinical asset, 4SC-208. 4SC also has several partners including Yakult Honsha for resminostat in Japan.

Stock data

Market cap.€144.7m
Last close€4.72
High / Low (52 weeks)€5.7 / €2.3
Stock market listingDE
Forecast net cash (€m)35.3
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual(4.8)8.390.9
Relative *(5.3)0.955.9

* % Relative to local index

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Company news

4SC AG raises €41m

Sun, 09 Jul 2017 16:41:15 GMT

Wellington Partners backs German biotech company 4SC AG

Wed, 08 Jul 2015 14:53:08 GMT

4SC Signs Licensing and Development Agreement with Menarini for Resminostat in ...

Thu, 16 Apr 2015 11:48:45 GMT

Stock Concentration on 4SC AG (VSC.DE) Shares

Tue, 21 Nov 2017 04:52:30 GMT

4SC and Yakult Honsha Announce Exclusive License Agreement for Japan for the ...

Thu, 14 Apr 2011 06:56:15 GMT

Investment summary

4SC’s new core strategy revealed earlier this year has focused on dermato-oncological indications, while its assets for other indications are partnered. The sharp focus will allow 4SC to become an expert in the field and to accumulate commercial know-how, as the company intends to market the core assets (resminostat, 4SC-202 and 4SC-208) in orphan indications on its own. A successful fund-raise in July means that the company now has sufficient funds until 2020 and past several important R&D events. We have overhauled our model to reflect 4SC’s new strategy and our new valuation is €344m or €11.2/share.

Last updated on 30/10/2017

Y/E Dec Revenue (€m) EBITDA (€m) PBT (€m) EPS (c) P/E (x) P/CF (x)
2015A 3.3 (7.9) (8.4) (58.58) N/A N/A
2016A 2.1 (10.9) (10.9) (54.17) N/A N/A
2017E 2.4 (14.5) (14.5) (55.74) N/A N/A
2018E 2.7 (17.0) (17.1) (53.57) N/A N/A

Last updated on 30/10/2017

Latest video

Executive interview - 4SC

Industry outlook

Resminostat could become the first HDAC inhibitor to gain EU approval for CTCL (vs two HDACs approved in the US). CTCL has been validated as a target indication for HDACs, with vorinostat (Merck & Co) and romidepsin (Celgene) FDA-approved on Phase II data.

Last updated on 03/10/2017

Key management

Jason Loveridge, CEO
Dr. Anna Niedl , Manager Corporate Communications and Investor

Company address

Am Klopferspitz 19a
82152
Planegg-Martinsried
Germany
+49 (0)89 700763-0
View website