Celyad (CYAD)

Business description

Celyad is developing an innovative Natural Killer Receptor CAR T-cell therapy (CYAD-01). This targets targets five solid and two hematologic cancers in the THINK study. A colorectal cancer study with chemotherapy (SHRINK) is underway.

Stock data

Market cap.€241.1m
Last close€24.42
High / Low (52 weeks)€54.0 / €22.9
Stock market listingEU
Forecast net cash (€m)36.2
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual(4.6)(28.7)(33.9)
Relative *(4.2)(27.9)(33.2)

* % Relative to local index

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Company news

Celyad SA (CYAD) Prices 523K ADS Allocation of 1.8M Share Global Offering at ...

Thu, 17 May 2018 13:07:30 GMT

BRIEF-Celyad Announces Pricing Of 47.3 Million Dollars Global Offering

Thu, 17 May 2018 13:07:30 GMT

Celyad SA (CYAD) to Offer 1.8M Shares

Tue, 15 May 2018 20:03:45 GMT

Celyad SA (CYAD) Announces THINK Study Case Report of CYAD-01 Induced Complete ...

Fri, 27 Apr 2018 09:45:00 GMT

Celyad to Present at the 29th Annual Piper Jaffray Healthcare Conference

Tue, 21 Nov 2017 21:22:30 GMT

Y/E Dec Revenue (€m) EBITDA (€m) PBT (€m) EPS (c) P/E (x) P/CF (x)
2015A 0.0 (27.8) (27.6) (317.0) N/A N/A
2016A 8.5 (24.1) (22.8) (209.0) N/A N/A
2017E 8.3 (26.7) (27.2) (286.0) N/A N/A
2018E 9.0 (24.7) (25.2) (265.0) N/A N/A

Last updated on 12/04/2018

Investment summary

Celyad has seen a near complete response with "clinical validity" in an AML patient treated with CYAD-01 NKR CAR T-cell therapy in the THINK trial. As two stable disease cases in colorectal cancer have also been seen plus ovarian responses, Celyad has identified AML and colorectal cancer as lead development indications. Cash on 30 December was €34m due to last into H119. A comprehensive clinical development trial plan has been announced especially looking at combination therapy approaches. The LINK and SHRINK studies have started.

Last updated on 27/04/2018

Industry outlook

The CART therapeutic area remains a hot area for investment with two major acquisitions. Sales of Yescarta (Gilead) and Kymriah (Novartis) may be slow to develop due to reimbursement delays. Bluebird is the leader in Multiple myeloma. Celyad's NKR CAR T-cells have shown initial promise in AML and mCRC. Celyad also has a leading IP position in allogeneic therapy and a Novartis deal. Immunocore has excellent technology in T-cell receptor therapy.

Last updated on 27/04/2018

Key management

Michel Lussier, Chairman
Dr Christian Homsy, CEO
Patrick Jeanmart, CFO
Dr Gaëtane Metz, COO

Company address

Rue Edouard Belin 12
1435 Mont-Saint-Guibert
Belgium
+32(0)10 39 41 00
View website