Kazia Therapeutics (KZA)

Business description

Kazia Therapeutics (formerly known as Novogen) has two clinical stage anti-cancer drugs GDC-0084 (targeting glioblastoma) and Cantrixil (targeting ovarian cancer) and a discovery-stage anti-tropomyosins program. GDC-0084 was inlicensed from Genentech, and Kazia is seeking other in-licence opportunities.

Stock data

Market cap.A$27m
Last closeA$0.55
High / Low (52 weeks)A$ / A$
Stock market listingAU
Forecast net cash (A$m)2.8
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual41.034.1(34.5)
Relative *48.238.3(36.9)

* % Relative to local index

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Company news

Kazia Therapeutics shares boom in New York after orphan drug status news

Fri, 23 Feb 2018 14:26:15 GMT

Novogen becomes Kazia Therapeutics

Mon, 20 Nov 2017 06:33:45 GMT

What's Ahead for Kazia Therapeutics Limited (KZIA) After Today's Big Increase?

Sat, 24 Feb 2018 20:34:36 GMT

Kazia Therapeutics Ltd. ADR

Fri, 24 Nov 2017 12:39:23 GMT

BRIEF-Kazia Therapeutics And Noxopharm Announce Collaboration

Tue, 26 Dec 2017 23:03:45 GMT

Y/E Jun Revenue (A$m) EBITDA (A$m) PBT (A$m) EPS (c) P/E (x) P/CF (x)
2016A 3.7 (10.6) (11.6) (28.44) N/A N/A
2017A 8.6 (10.2) (10.9) (22.81) N/A N/A
2018E 4.0 (11.0) (12.2) (25.25) N/A N/A
2019E 13.6 (4.8) (6.3) (13.07) N/A N/A

Last updated on 21/12/2017

Investment summary

Kazia Therapeutics (formerly Novogen) is developing two groups of anti-cancer compounds, including GDC-0084, a phase II-ready PI3K inhibitor licensed from Genentech that is intended for glioblastoma. The company has transferred the IND from Genentech and is undertaking final preparations for a Phase II study expected to start in Q417; an initial dose-optimisation study will precede a randomised trial in 228 first-line glioblastoma patients. It is undertaking a Phase I trial of its super-benzopyran drug Cantrixil, and has outlicensed its preclinical super-benzopyran program to Heaton-Brown Life Sciences. The 60-patient Phase I trial of Cantrixil in ovarian cancer which commenced in December 2016 is expected to report MTD in Q118; while the primary aim is to assess safety and tolerability, radiological responses and biomarkers will be assessed for indications of efficacy. Kazia has initiated a next-generation anti-tropomyosin drug discovery program supported by an A$3m government grant. The company had A$11.5m cash at June 2017.

Last updated on 02/02/2018

Industry outlook

Kazia Therapeutics is a biotechnology company listed on the ASX and NASDAQ. Its two main drug technology platforms are super-benzopyrans (SBP) and a PI3K inhibitor. SBP compounds show potent activity against cancer stem cells.

Last updated on 02/02/2018

Key management

Iain Ross, Chairman
James Garner, CEO

Company address

16-20 Edgeworth David Ave
Hornsby
NSW 2077
Australia
(+61 2) 9476 0344
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