Achillion Pharmaceuticals (ACHN)

Business description

Achillion is engaged in the discovery and development of treatments for chronic HCV and progressing compounds from its research platform in its novel factor D programme. It is collaborating with J&J to develop and commercialise its HCV franchise, including a triple-regimen treatment, which is potentially best in class.

Stock data

Market cap.US$590.7m
Last closeUS$4.32
High / Low (52 weeks)US$9.3 / US$3.2
Stock market listingUS
Forecast net cash (US$m)320.7
Forecast gearing ratio (%)N/A
SectorPharmaceutical & healthcare

Price performance

Relative *(5.6)12.4(56.3)

* % Relative to local index

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Company news

Is the Options Market Predicting a Spike in Achillion Pharmaceuticals (ACHN ...

Thu, 20 Jul 2017 13:30:00 GMT

Achillion Pharmaceuticals, Inc. (ACHN) Upgraded to “Hold” by Zacks Investment ...

Sat, 22 Jul 2017 14:09:01 GMT

Investors Are Circling Achillion Pharmaceuticals, Inc. (NasdaqGS:ACHN), What ...

Sat, 22 Jul 2017 15:00:00 GMT

Stock under Review -: Achillion Pharmaceuticals, Inc. (ACHN)

Fri, 21 Jul 2017 10:41:15 GMT

Investors Set Sail on Valuation For Achillion Pharmaceuticals, Inc. (NasdaqGS ...

Sat, 22 Jul 2017 15:00:00 GMT

Y/E Dec Revenue (US$m) EBITDA (US$m) PBT (US$m) EPS (c) P/E (x) P/CF (x)
2015A 66.1 (4.3) (3.9) (3.11) N/A 122.1
2016A 15.0 (52.9) (50.7) (37.10) N/A N/A
2017E 0.0 (85.9) (85.0) (59.24) N/A N/A
2018E 0.0 (89.2) (89.2) (59.18) N/A N/A

Last updated on 11/05/2017

Investment summary

Achillion is developing an oral, once-a-day, single pill treatment for HCV more competitive than leader Harvoni. The company recently reported a 100% SVR rate in patients who received just 6-8 weeks of therapy in a Phase IIa study evaluating the combination of AL-335, Odalasvir (ACH-3102), and Simeprevir in genotype 1 HCV. Partner Janssen initiated a Phase IIb trial in November 2016. Achillion is well funded to progress its oral factor-D programme in rare diseases, such as PNH and C3 Glomerulopathy, as well as in larger market opportunities including dry AMD. Patient dosing in a Phase II trial in PNH for its factor-D inhibitor candidate, ACH-4471, has been initiated with interim results expected in Q217.

Last updated on 01/06/2017

Industry outlook

More than 150m people are infected with HCV worldwide. Treatment has been transformed in recent years by the approval of Sovaldi (sofosbuvir) and Gilead's combination product; recent pressure from key healthcare groups has led to a drop in HCV prices.

Last updated on 01/06/2017

Key management

Milind S. Deshpande, CEO
Mary Kay Fenton, CFO
David Apelian, EVP and CMO
Joseph Truitt, EVP of business development and chief commerc

Company address

300 George Street
New Haven
United States
View website