Alexza Pharmaceuticals (ALXA)

Business description

Alexza develops products for the acute treatment of CNS disorders using its proprietary Staccato rapid inhalation drug delivery system. Adasuve is approved (US and EU) for the acute treatment of agitation in patients with schizophrenia or bipolar I disorder.

Stock data

Market cap.US$20.3m
Last closeUS$0.94
High / Low (52 weeks)US$1.5 / US$0.3
Stock market listingUS
Forecast net debt (US$m)79.8
Forecast gearing ratio (%)88
SectorPharmaceutical & healthcare

Price performance

Relative *0.184.0(24.8)

* % Relative to local index

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Y/E Dec Revenue (US$m) EBITDA (US$m) PBT (US$m) EPS (c) P/E (x) P/CF (x)
2014A 5.6 (34.1) (45.1) (253.85) N/A N/A
2015A 5.0 (37.0) (49.3) (248.91) N/A N/A
2016E 2.5 (16.5) (25.8) (117.44) N/A N/A
2017E 7.2 (19.9) (34.6) (150.81) N/A N/A

Last updated on 28/09/2016

Investment summary

Alexza markets Adasuve (Staccato loxapine), as well as further opportunities from new product candidates that apply the validated Staccato platform for rapid drug delivery. Approved for acute agitation in adults with schizophrenia or bipolar disorder, Adasuve was launched in 20 countries in the EU and Latin America by Ferrer, and Alexza recently regained US rights from Teva. Adasuve offers speed, dosing reliability and ease of administration advantages vs established anti-agitation treatments. AZ-002 (Staccato alprazolam) is also undergoing a Phase IIa study for acute repetitive seizures, and positive interim data were released in late 2015.

Last updated on 11/10/2016

Industry outlook

Alexza has been undergoing a strategic review since autumn 2015, and on 10 May it announced that it had entered into an agreement whereby Ferrer would acquire Alexza for $0.90 per share, plus contingent value rights providing up to an additional $35m (approximately $1.60 per share) based on the achievement of milestones for Staccato-based products.

Last updated on 11/10/2016

Key management

Thomas King, CEO
Ana Kapor, Senior Director, Investor Relations and Corpo

Company address

2091 Stierlin Court
Mountain View
CA 94043
United States
(650) 944-7000
View website