Atossa Genetics (ATOS)

Business description

Based in Seattle, WA, Atossa Genetics is focused on the development of locally administered pharmaceuticals for the treatment of pre-cancer and early-stage breast cancer. Lead candidate afimoxigene topical gel is expected to start a Phase II study in 2016 in breast hyperplasia or DCIS.

Stock data

Market cap.US$19.9m
Last closeUS$0.63
High / Low (52 weeks)US$1.6 / US$0.2
Stock market listingUS
Forecast net cash (US$m)6.1
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual140.685.1(58.9)
Relative *144.575.2(64.7)

* % Relative to local index

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Company news

Y/E Dec Revenue (US$m) EBITDA (US$m) PBT (US$m) EPS (c) P/E (x) P/CF (x)
2015A 0.0 (9.5) (9.8) (514.81) N/A N/A
2016A 0.0 (6.9) (7.2) (245.98) N/A N/A
2017E 0.0 (7.7) (7.8) (82.72) N/A N/A
2018E 0.0 (11.4) (11.5) (43.40) N/A N/A

Last updated on 08/12/2017

Investment summary

Atossa is advancing endoxifen, a metabolite of tamoxifen, as a topical treatment for high mammographic breast density (MBD), a condition associated with higher cancer risk. It recently reported positive Phase I safety data for both formulations. Atossa is also developing oral endoxifen as well as a potential treatment for breast cancer patients refractory to tamoxifen. About 20-25% of the 1.0m women taking tamoxifen worldwide develop resistance to it, and have an increased risk for cancer recurrence. Atossa is also advancing its proprietary intraductal microcatheter (IDMC), intended to selectively introduce drugs to breast ducts to improve drug targeting. It is combining its IDMC with established cancer drug fulvestrant and started a Phase II trial in 2016.

Last updated on 02/02/2018

Industry outlook

Atossa's programs may fall under the 505(b)2 development pathway, which would reduce the breadth of data needed to support a marketing application. The firm plans to start Phase II trials for oral and topical endoxifen in Q118. Atossa had $2.8 net cash at Q317, and raised $5.5m in an equity offering in Q417, which we estimate extends its runway into mid-2018.

Last updated on 02/02/2018

Key management

Steven Quay , CEO
Kyle Guse, CFO

Company address

2300 Eastlake Ave E
Suite 200
Seattle
WA 98102
United States
View website