Biondvax Pharmaceuticals (BVXV)

Business description

Biondvax is developing a potentially universal influenza vaccine and the lead candidate M-001 could be positioned as a primer for seasonal or pandemic vaccines or as a standalone influenza vaccine. So far M-001 has been tested in two Phase I/II and three Phase II trials and consistently demonstrated immunogenicity to multiple virus strains.

Stock data

Market cap.NIS81.9m
Last closeNIS0.49
High / Low (52 weeks)NIS0.6 / NIS0.3
Stock market listingTel Aviv Stock Exchange
Forecast net cash (NISm)24.6
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual(8.1)47.035.9
Relative *(6.7)47.837.1

* % Relative to local index

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Y/E Dec Revenue (NISm) EBITDA (NISm) PBT (NISm) EPS (NIS) P/E (x) P/CF (x)
2014A 0.0 (7.5) (7.8) (0.14) N/A N/A
2015A 0.0 (10.7) (10.2) (0.10) N/A N/A
2016E 0.0 (10.7) (10.7) (0.08) N/A N/A
2017E 0.0 (10.7) (10.8) (0.08) N/A N/A

Last updated on 10/02/2017

Investment summary

BiondVax with its epitope-based multimeric vaccine candidate M-001 is among the leaders in the development of the universal influenza vaccine worldwide. M-001 has so far been tested in two Phase I/II and three Phase II trials involving 479 participants in total and was shown to be consistently safe, immuno-genic and demonstrated synergy with conventional flu vaccines. The readout from the ongoing European Phase II study is due in coming months, while the initiation of the last Phase IIb study funded by the US National Institutes of Health (NIH), with results likely in H217/H118, will pave the way for partnering and the Phase III programme. In January 2017, Angels High Tech investments agreed to invest NIS10.9m ($2.83m) in exchange for 20% stake (after the investment). This adds to BiondVax's net cash position of NIS29.7m ($8.0m) at end-Q316.

Last updated on 02/03/2017

Industry outlook

Current influenza vaccines are solely strain specific, needs to be updated every year with the effectiveness still lingering around 40%. There is a clear need for a more reliable vaccine that is both more immunoprotective and with coverage against a wider range of flu strains for the entire population and in particular for the elderly.

Last updated on 02/03/2017

Key management

Uri Ben Or, CFO

Company address

14 Einstein Street
Ness Ziona
7403618
Israel
+972 8 930 2529
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