C4X Discovery Holdings (C4XD)

Business description

C4X Discovery is a UK business using its proprietary NMR-based technology to enable rational drug design, aimed at selecting safer and better drugs in a reduced timeframe. An OX1 receptor antagonist is the lead pre-clinical candidate.

Stock data

Market cap.£41m
Last close88.00p
High / Low (52 weeks)117.5p / 84.0p
Stock market listingLN
Forecast net debt (m)N/A
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual0.0(2.8)(24.5)
Relative *(0.2)(7)(32.8)

* % Relative to local index

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Company news

C4X to raise up to £7mln through a share placing

Tue, 14 Mar 2017 09:33:45 GMT

C4X Discovery strengthens drug discovery alliance with Evotec

Wed, 28 Sep 2016 07:31:52 GMT

C4X Discovery Holdings PLC bags a billion molecules (virtually)

Tue, 12 Jul 2016 14:59:37 GMT

C4X Discovery to focus on early stage licensing deals

Fri, 06 Jan 2017 08:07:23 GMT

Zeus Capital Q&A with Dr Gary Waanders: C4X Discovery Holdings PLC (LON:C4XD)

Tue, 10 Jan 2017 11:46:13 GMT

Y/E Jul Revenue (£m) EBITDA (£m) PBT (£m) EPS (p) P/E (x) P/CF (x)
2015A 0.3 (3.8) (3.8) (10.75) N/A N/A
2016A 0.3 (6.7) (6.7) (16.66) N/A N/A
2017E N/A N/A N/A N/A N/A N/A
2018E N/A N/A N/A N/A N/A N/A

Last updated on 11/05/2017

Investment summary

C4X Discovery’s (C4XD) proprietary drug discovery platform aims to become a highly efficient and productive discovery R&D engine. The Orexin programme, a selective OX1 antagonist, is the lead candidate, currently pre-clinial. Recently acquired proprietary human genetic technology platform (Taxonomy3) and Molplex technologies, broadens its drug discovery capabilities to both target identification and lead generation. In September 2016, C4X announced a strategic collaboration with Evotec, building on a previous agreement. The agreement is a risk-shared multi-target programme. This is a positive development and in combination with the recently announced £7m fundraise (before expenses), it enables C4X to progress the outputs from its drug discovery engine and its preclinical pipeline.

Last updated on 01/06/2017

Industry outlook

C4XD's NMR-based technology can be used to solve the 3-D conformations of biomolecules in solution, which the company believes will enable data-driven rational design of superior drug candidates, on a significantly faster timescale than conventional techniques, which should appeal to the global pharma industry. Existing partnerships (Evotec, AstraZeneca and Takeda) and the Structural Genomics Consortium collaboration provide external validation of the technology.

Last updated on 01/06/2017

Key management

Dr Clive Dix, Chairman & CEO

Company address

Manchester One
Portland Street
Manchester
M1 3L
United Kingdom
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