Genkyotex (GKTX )

Business description

Genticel and privately-held company Genkyotex have signed a contribution agreement to form a combined entity focused on the development of NOX inhibitors for fibrosis and other indications. The transaction has been approved by Genticel’s shareholders.

Stock data

Market cap.€157.3m
Last close€2.02
High / Low (52 weeks)€5.2 / €1.3
Stock market listingEU
Forecast net debt (m)N/A
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual3.6(6.5)(55.5)
Relative *2.0(15.4)(62.8)

* % Relative to local index

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Company news

BRIEF-Genticel becomes Genkyotex

Tue, 28 Feb 2017 17:26:15 GMT

BRIEF-As of March 31, Genkyotex cash & cash equivalents were EUR 21.8 million

Thu, 27 Apr 2017 17:37:30 GMT

Genkyotex Announces FDA Approval of IND for Phase 2 Trial of GKT831 in ...

Tue, 02 May 2017 19:07:30 GMT

BRIEF-Genticel and Genkyotex intend to enter into strategic combination

Thu, 22 Dec 2016 12:29:15 GMT

Genkyotex Provides Business Update for Q1 2017

Thu, 27 Apr 2017 16:47:32 GMT

Revenue (£m) EBITDA (£m) PBT (£m) EPS (p) P/E (x) P/CF (x)
2016A N/A N/A N/A N/A N/A N/A
2017A N/A N/A N/A N/A N/A N/A
2018E N/A N/A N/A N/A N/A N/A
2019E N/A N/A N/A N/A N/A N/A

Investment summary

Genticel and Genkyotex have agreed to enter into a strategic collaboration. This shifts the focus to NOX science and the development of small molecule NOX inhibitors for fibrosis and inflammation. Lead product GKT831 will start a Phase II clinical trial in primary biliary cholangitis (PBC) in H117 with data in 2018. Second product GKT771 will start a Phase I study in H217 and focus on inflammation and angiogenesis. The company also has a portfolio of early stage NOX inhibitors for oncology, hearing loss and neurology indications. The new company will continue the partnership established by Genticel with the Serum Institute of India Ltd (SIIL) which involves up to $57m of milestone payments and single-digit royalties on net sales. Estimated cash of the combined entity is €27m in early 2017, sufficient until 2018.

Last updated on 02/05/2017

Industry outlook

The new company is focused on NOX science, an enzyme complex that generates reactive oxygen species (ROS). Increased NOX activity has been linked to various diseases; in particular to metabolic and cardiovascular diseases and neurodegeneration.

Last updated on 02/05/2017

Key management

Elias Papatheodorou, CEO
Philippe Wiesel, Executive VP & Chief Medical Officer
Benedikt Timmerman, Deputy CEO

Company address

516 Rue Pierre et Marie Curie
Prologue Biotech
Labège-Innopole
31670
France
+33 (0)1 53 67 36 77
View website