Hybrigenics (ALHYG)

Business description

Hybrigenics is a French biotech company. It provides protein-protein and small molecule analysis services and is conducting anti-cancer studies on lead drug inecalcitol, primarily in adult leukaemias.

Stock data

Market cap.€28.6m
Last close€0.80
High / Low (52 weeks)€1.1 / €0.7
Stock market listingAL
Forecast net cash (€m)6.8
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual(9.1)(3.6)(10.1)
Relative *(11.4)(7.6)(20.9)

* % Relative to local index

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Company news

BRIEF-Hybrigenics announces results from Phase II study on inecalcitol

Thu, 09 Feb 2017 17:26:15 GMT

Proteomics Markets for Research and IVD Applications (Mass Spectrometry ...

Tue, 23 Sep 2014 15:56:15 GMT

Chronic Lymphocytic Leukemia (CLL) Market H2 2016 covering Companies ...

Mon, 05 Dec 2016 05:03:50 GMT

South Africa's Ascendis Health buys two European firms, shares rise

Tue, 24 May 2016 07:52:30 GMT

Institut Pasteur Appoints Isabelle Buckle, EVP, Research Applications and ...

Mon, 01 Dec 2014 08:03:45 GMT

Y/E Dec Revenue (€m) EBITDA (€m) PBT (€m) EPS (c) P/E (x) P/CF (x)
2014A 6.8 (2.1) (2.2) (8.5) N/A N/A
2015A 6.5 (3.8) (3.9) (11.4) N/A N/A
2016E 7.5 (4.3) (4.2) (11.8) N/A N/A
2017E 8.0 (4.4) (4.4) (12.4) N/A N/A

Last updated on 09/02/2017

Investment summary

Hybrigenics has adopted a development strategy with vitamin D3 derivative inecalcitol, first focusing on adult haematological cancers. In addition to chronic lymphocytic leukaemia (CLL) and chronic myeloid leukaemia (CML), Hybrigenics is prioritising acute myeloid leukaemia (AML) given inecalcitol's orphan status in the US and Europe and the scarcity of treatment options in this aggressive and difficult to treat leukaemia. The investment case rests on inecalcitol’s potential to enhance rather than replace approved therapies, particularly with inecalcitol's benign safety profile. Our peak sales estimate is US$769m. Cash at end June 2016 stood at €8.4m.

Last updated on 02/03/2017

Industry outlook

An international Phase II study in AML has started recruiting patients in France and the US in H2 2016. Interim Phase II data are expected in late 2016 or early 2017 in CML. The collaboration with Servier on ubiquitin-specific proteases is ongoing and the company received a milestone payment of €1.5m during H116. Hybrigenics has presented in vitro results on inecalcitol in multiple myeloma and acute myeloid leukemia on 4th December at the annual ASH meeting in San Diego, USA.

Last updated on 02/03/2017

Key management

Daan Ellens, Chairman
Rémi Delansorne, CEO
Guillaume Floch, CFO

Company address

3-5 impasse Reille
75014
Paris
France
01 58 10 38 00
View website