Medigene (MDG1)

Business description

Medigene is a German biotech company with a core business in cancer immunotherapy. Dendritic cell (DC) vaccines are in Phase I/II clinical studies, while a T-cell receptor (TCR) candidate should enter the clinic in 2018.

Stock data

Market cap.€373.5m
Last close€16.75
High / Low (52 weeks)€17.4 / €8.9
Stock market listingDE
Forecast net cash (€m)49.8
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual28.556.725.2
Relative *37.364.719.6

* % Relative to local index

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Company news

Medigene AG: Addressing The CAR-T Market Pain Points

Wed, 18 Mar 2015 16:55:29 GMT

Medigene AG to be included in TecDAX Index

Tue, 06 Dec 2016 10:18:45 GMT

Medigene announces outlicensing of AAVLP technology

Tue, 20 Dec 2016 06:22:30 GMT

MEDIGENE AG (OTCMKTS:MDGEF) on Focus After Report of More Shorts

Wed, 14 Feb 2018 22:07:30 GMT

Medigene Keeps Eyes On Immunotherapy Prize

Tue, 22 Dec 2015 18:35:23 GMT

Y/E Dec Revenue (€m) EBITDA (€m) PBT (€m) EPS (c) P/E (x) P/CF (x)
2015A 6.8 (9.4) (12.8) (73.55) N/A N/A
2016A 9.7 (10.2) (11.3) (55.51) N/A N/A
2017E 9.0 (17.6) (18.6) (88.63) N/A N/A
2018E 9.3 (19.5) (20.2) (91.11) N/A N/A

Last updated on 13/12/2017

Investment summary

Medigene is focused on the rapid development of its cancer immunotherapy technology platforms: dendritic cell (DC) cancer vaccines, adoptive T-cell therapy (TCR) and T-cell specific antibodies (TAB). Phase I/II studies are ongoing with DC vaccines for prostate cancer and acute myeloid leukaemia (investigator-sponsored) and acute myeloid leukaemia (Medigene). For TCRs, Medigene plans to receive approval for its first company led trial by year end. Important progress includes an alliance with bluebird bio, a prominent T-cell immunology company, to utilise its TCR technology platform to identify four therapeutic candidates against four targets. This is positive as it validates its TCR technology and offers potential upside from any development. Medigene is well-funded to execute its clinical programme, as of 30th September cash was €55.4m.

Last updated on 02/02/2018

Industry outlook

Cancer immunotherapy is attracting huge biotech investor interest. Medigene's DC vaccine technology is a new generation, with multiple potential efficacy and manufacturing benefits over the forerunners, eg Provenge. The TCR programme has similarities to CAR-T products, but with potentially significant efficacy and safety advantages.

Last updated on 02/02/2018

Key management

Prof. Horst Domdey, Chairman
Prof. Dr. Dolores Schendel, CEO
Thomas Taapken, CFO
Prof. Dr. Dolores Schendel, CEO

Company address

Lochhamer Str. 11
Martinsried
82152
Germany
+49-89-20 00 33 - 0
View website