Onxeo (ONXEO)

Business description

Onxeo is focused on orphan cancer and has three late-stage orphan oncology assets it could commercialise alone in Europe (Livatag, Beleodaq and Validive). Royalty-earning Beleodaq (belinostat) is launched in the US, along with two non-core, partnered, specialty products.

Stock data

Market cap.€75.4m
Last close€1.49
High / Low (52 weeks)€5.4 / €1.0
Stock market listingEU
Forecast net cash (€m)27.9
Forecast gearing ratio (%)N/A
SectorPharmaceutical & healthcare

Price performance

Relative *(6.7)41.0(43.1)

* % Relative to local index

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Company news

Onxeo: An Upcoming Mid-Sized Pharma With Ambitions

Thu, 12 Mar 2015 19:00:18 GMT

Onxeo Raises €12.5 Million through Capital Increase with US and European Investors

Fri, 30 Sep 2016 07:07:30 GMT

Onxeo finds a partner to progress its cancer medication

Wed, 13 Sep 2017 15:27:19 GMT

Onxeo Provides Financial Update

Wed, 14 Mar 2018 19:07:30 GMT

Onxeo to Present Results of Two Studies Highlighting Potential of AsiDNA™ as ...

Thu, 15 Mar 2018 07:36:22 GMT

Y/E Dec Revenue (€m) EBITDA (€m) PBT (€m) EPS (c) P/E (x) P/CF (x)
2015A 3.5 (20.4) (20.0) (43.53) N/A N/A
2016A 4.4 (21.3) (20.4) (44.64) N/A N/A
2017E 10.2 (15.1) (15.7) (24.02) N/A N/A
2018E 2.6 (13.6) (14.0) (27.79) N/A N/A

Last updated on 07/02/2018

Investment summary

Recently, Onxeo's AsiDNA demonstrated the first preclinical PoC data showing potential to be administrated intravenously. Another dataset showed that AsiDNA in combination with its Beleodaq (belinostat) had synergistic effect on suppressing malignant cell growth in various cancers, while having no effect on healthy cells. AsiDNA, a first-in-class DNA repair inhibitor, has already been tested in a Phase I trial in melanoma with promising safety and initial efficacy results. Onxeo aims to initiate a Phase I trial in solid tumours in 2018. The company is also analyzing the full data from its Phase III trial with Livatag, which did not meet primary endpoints, and will decide further steps. In September 2017, Onxeo out-licensed its Phase III ready orphan oncology asset Validive to Monopar Therapeutics for a total deal value of $108m with up to double-digit royalties. Onxeo’s Beleodaq is already launched in the US with partner Spectrum for r/r peripheral T-cell lymphoma (r/r PTCL), generating royalties for Onxeo.

Last updated on 02/03/2018

Industry outlook

The patent expiry of blockbuster drugs and increased competition from generics has shifted the focus of the pharmaceutical industry to orphan drugs. Government support, as well as input from the regulatory bodies provide incentives for orphan drug developers.

Last updated on 02/03/2018

Key management

Judith Greciet, CEO
Nicolas Fellmann, CFO
Valérie Leroy, Director, Investor Relations & Corporate Com

Company address

49 Boulevard du Général Martial Valin
+33 (0)1 45 58 71 00
View website