Onxeo (ONXEO)

Business description

Onxeo is focused on orphan cancer and has three late-stage orphan oncology assets it could commercialise alone in Europe (Livatag, Beleodaq and Validive). Royalty-earning Beleodaq (belinostat) is launched in the US, along with two non-core, partnered, specialty products.

Stock data

Market cap.€65.5m
Last close€1.29
High / Low (52 weeks)€5.4 / €1.0
Stock market listingEU
Forecast net cash (€m)3.4
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual(6.5)(19.5)(59.8)
Relative *(8.3)(22.7)(61.4)

* % Relative to local index

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Company news

Y/E Dec Revenue (€m) EBITDA (€m) PBT (€m) EPS (fd) (c) P/E (x) P/CF (x)
2016A 4.4 (21.3) (20.4) (44.64) N/A N/A
2017A 9.5 (17.4) (19.7) (23.58) N/A N/A
2018E 2.6 (12.1) (12.2) (24.20) N/A N/A
2019E 3.9 (11.1) (11.2) (22.26) N/A N/A

Last updated on 27/04/2018

Investment summary

On 24 April, Onxeo announced that the first patient had been treated with AsiDNA, a first-in-class DNA break repair inhibitor, via systemic administration in the Phase I trial. AsiDNA has already generated supportive data from a Phase I trial in melanoma using intratumoural injection. Alongside the Phase I trial Onxeo is conducting a broad preclinical programme that explores AsiDNA in various settings and combinations with other drugs. Two abstracts with preclinical data were presented at the American Association for Cancer Research conference in April potentially demonstrating unique characteristics of its mechanism of action. Our valuation is marginally higher at €221m or €4.4/sh.

Last updated on 27/04/2018

Industry outlook

The patent expiry of blockbuster drugs and increased competition from generics has shifted the focus of the pharmaceutical industry to orphan drugs. Government support, as well as input from the regulatory bodies provide incentives for orphan drug developers.

Last updated on 27/04/2018

Key management

Judith Greciet, CEO
Nicolas Fellmann, CFO
Valérie Leroy, Director, Investor Relations & Corporate Com

Company address

49 Boulevard du Général Martial Valin
Paris
75015
France
+33 (0)1 45 58 71 00
View website