Onxeo (ONXEO)

Business description

Onxeo is focused on orphan cancer and has three late-stage orphan oncology assets it could commercialise alone in Europe (Livatag, Beleodaq and Validive). Royalty-earning Beleodaq (belinostat) is launched in the US, along with two non-core, partnered, specialty products.

Stock data

Market cap.€119m
Last close€2.53
High / Low (52 weeks)€3.7 / €2.3
Stock market listingEU
Forecast net cash (€m)1.6
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual1.2(5.9)(28.5)
Relative *(0.2)(10.2)(35.7)

* % Relative to local index

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Company news

Reprimand to Onxeo SA

Tue, 21 Feb 2017 09:56:15 GMT

Onxeo: An Upcoming Mid-Sized Pharma With Ambitions

Thu, 12 Mar 2015 19:00:18 GMT

Onxeo Receives the EnterNext Tech 40 Label

Thu, 20 Apr 2017 18:22:30 GMT

Onxeo SA: Combination of AsiDNA and PARP Inhibitors Demonstrates Synergistic ...

Wed, 07 Sep 2016 15:56:15 GMT

Positive DSMB Recommendation to Continue Livatag® ReLive Phase III Trial in HCC

Mon, 21 Nov 2016 17:01:31 GMT

Y/E Dec Revenue (€m) EBITDA (€m) PBT (€m) EPS (c) P/E (x) P/CF (x)
2015A 3.5 (20.4) (20.0) (43.53) N/A N/A
2016A 4.4 (21.2) (20.4) (48.04) N/A N/A
2017E 7.9 (21.7) (21.7) (46.33) N/A N/A
2018E N/A N/A N/A N/A N/A N/A

Last updated on 20/03/2017

Investment summary

According to recent news, ReLive, the 390-patient Phase III trial with Livatag for hepatocellular carcinoma, which began in 2012, is now fully enrolled. The preliminary efficacy data are expected in mid-2017. With its FY16 results, Onxeo reported that other R&D projects are progressing according to plan, including the development of the first-in-class AsiDNA, a signal-interfering DNA repair technology, which should move into clinic in 2017. A preclinical study showed that AsiDNA could potentially be combined with existing PARP inhibitors. Onxeo’s third lead asset, Beleodaq, is already launched in the US with partner Spectrum for relapsed/refractory peripheral T-cell lymphoma (r/r PTCL), generating royalty income for Onxeo. In September Onxeo raised gross €12.5m boosting its cash position, which was €29.2m at end-2016.

Last updated on 04/04/2017

Industry outlook

The patent expiry of blockbuster drugs and increased competition from generics has shifted the focus of the pharmaceutical industry to orphan drugs. Government incentives for drug development, as well as support from the regulatory bodies provide incentives for orphan drug developers.

Last updated on 04/04/2017

Key management

Judith Greciet, CEO
Nicolas Fellmann, CFO
Valérie Leroy, Director, Investor Relations & Corporate Com

Company address

49 Boulevard du Général Martial Valin
Paris
75015
France
+33 (0)1 45 58 71 00
View website