Onxeo (ONXEO)

Business description

Onxeo is focused on orphan cancer and has three late-stage orphan oncology assets it could commercialise alone in Europe (Livatag, Beleodaq and Validive). Royalty-earning Beleodaq (belinostat) is launched in the US, along with two non-core, partnered, specialty products.

Stock data

Market cap.€72m
Last close€1.42
High / Low (52 weeks)€5.4 / €1.4
Stock market listingEU
Forecast net cash (€m)1.6
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual(26.0417)(62.0321)(43.8735)
Relative *(28.0621)(63.5173)(53.3446)

* % Relative to local index

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Company news

Onxeo Reports First Instance Decision from the Commercial Court of Paris in ...

Tue, 17 Oct 2017 19:52:30 GMT

Onxeo: An Upcoming Mid-Sized Pharma With Ambitions

Thu, 12 Mar 2015 19:00:18 GMT

Onxeo Raises €12.5 Million through Capital Increase with US and European Investors

Fri, 30 Sep 2016 07:07:30 GMT

Onxeo announces compelling preclinical data in combination for its two ...

Thu, 28 Sep 2017 06:00:00 GMT

Onxeo finds a partner to progress its cancer medication

Wed, 13 Sep 2017 15:22:30 GMT

Y/E Dec Revenue (€m) EBITDA (€m) PBT (€m) EPS (c) P/E (x) P/CF (x)
2015A 3.5 (20.4) (20.0) (43.53) N/A N/A
2016A 4.4 (21.2) (20.4) (48.04) N/A N/A
2017E 7.9 (21.7) (21.7) (46.33) N/A N/A
2018E N/A N/A N/A N/A N/A N/A

Last updated on 15/09/2017

Investment summary

Onxeo's Phase III asset Livatag did not meet the primary overall survival endpoint compared to standard of care arm, where survival was unexpectedly high. Onxeo is now analyzing the full data set to decide further steps. On a more positive note Onxeo out-licensed its Phase III ready orphan oncology asset Validive to Monopar Therapeutics for a total deal value of $108m with up to double-digit royalties. Recently, Onxeo's AsiDNA demonstrated first preclinical PoC data showing potential to be administrated intravenously. AsiDNA, a first-in-class DNA repair inhibitor, has already been tested in a Phase I trial in melanoma with promising safety and initial efficacy results. Onxeo aims to file the investigational new drug application by end-2017 and will explore AsiDNA's potential in combination with PARP inhibitors. Onxeo’s Beleodaq is already launched in the US with partner Spectrum for r/r peripheral T-cell lymphoma (r/r PTCL), generating royalties for Onxeo.

Last updated on 03/10/2017

Industry outlook

The patent expiry of blockbuster drugs and increased competition from generics has shifted the focus of the pharmaceutical industry to orphan drugs. Government support, as well as input from the regulatory bodies provide incentives for orphan drug developers.

Last updated on 03/10/2017

Key management

Judith Greciet, CEO
Nicolas Fellmann, CFO
Valérie Leroy, Director, Investor Relations & Corporate Com

Company address

49 Boulevard du Général Martial Valin
Paris
75015
France
+33 (0)1 45 58 71 00
View website