Orexigen Therapeutics (OREX)

Business description

Orexigen is a biopharmaceutical company focusing on obesity treatments. It will sell its sole product, Contrave, through its own salesforce in the US after taking back the rights from partner, Takeda. Contrave was launched in the US in Oct 2014 and approved in the EU in March 2015 under the trade name Mysimba.

Stock data

Market cap.US$32.7m
Last closeUS$2.12
High / Low (52 weeks)US$5.4 / US$1.7
Stock market listingUS
Forecast net debt (US$m)132.2
Forecast gearing ratio (%)147
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual(9.4)(31.4)(38.6)
Relative *(11.2)(33.2)(46.5)

* % Relative to local index

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Company news

Orexigen Therapeutics Announces Commercialization and Distributorship ...

Thu, 08 Dec 2016 12:22:30 GMT

Orexigen Therapeutics Announces Second Quarter 2017 Financial Results

Tue, 08 Aug 2017 20:03:45 GMT

Orexigen Therapeutics Reports Financial Results for the Fourth Quarter and ...

Tue, 28 Mar 2017 20:15:00 GMT

Orexigen Therapeutics to Present at the 35th Annual JP Morgan Healthcare ...

Mon, 19 Dec 2016 12:41:32 GMT

Orexigen Therapeutics Announces Expansion of Distributorship Agreement with ...

Wed, 26 Jul 2017 12:52:26 GMT

Y/E Dec Revenue (US$m) EBITDA (US$m) PBT (US$m) EPS (c) P/E (x) P/CF (x)
2015A 24.5 (60.3) (67.3) (523.81) N/A N/A
2016A 33.7 (134.6) (138.1) (972.82) N/A N/A
2017E 94.0 (138.3) (141.4) (796.12) N/A N/A
2018E 160.3 (68.1) (72.7) (467.47) N/A N/A

Last updated on 17/08/2017

Investment summary

Orexigen’s obesity drug, Contrave, is an extended-release oral combination of long-marketed bupropion (Wellbutrin for depression) and Naltrexone (Revia for addiction). Now the leading branded obesity treatment in the US, Orexigen announced the acquisition of US rights to Contrave in the US from partner Takeda in mid-March 2016. The company is now marketing the drug with a new dedicated salesforce of 160 reps with a focus on the consumer. Contrave is approved under the brand Mysimba in most international markets. It has now launched in 17 countries, including South Korea, Spain, Poland, UK and Ireland. Launches in an additional 10-15 countries are expected by Q118.

Last updated on 06/09/2017

Industry outlook

Orexigen is a biopharmaceutical company focusing on obesity treatments. Contrave was launched in the US in October 2014 and approved in the EU in March 2015, under the trade name Mysimba.

Last updated on 06/09/2017

Key management

Jason Keyes, CFO

Company address

3344 N. Torrey Pines Court
Suite 200
La Jolla
CA 92037
United States
(858) 875-8600
View website