Pluristem Therapeutics (PSTI)

Business description

Pluristem is a biotech company, headquartered in Israel, focused on the development of cell-based therapeutics derived from placenta. The company is advancing PLX-PAD for critical limb ischemia (CLI) with a Phase III study on hip fracture. PLX-R18 is being advanced for acute radiation syndrome and hematopoietic cell transplant.

Stock data

Market cap.US$134.7m
Last closeUS$1.22
High / Low (52 weeks)US$2.0 / US$1.1
Stock market listingUS, Tel Aviv Stock Exchange
Forecast net cash (US$m)21.7
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual(11.3)(20.6)(13.8)
Relative *(14)(15.6)(24.2)

* % Relative to local index

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Company news

Pluristem and Indiana University to Initiate Joint Project Evaluating PLX-R18 ...

Mon, 23 Apr 2018 10:52:30 GMT

Pluristem Therapeutics Inc.: A Biotech Company Inspired By Life

Thu, 14 Sep 2017 11:38:07 GMT

Pluristem's PLX-R18 Improves Hematopoietic Transplantation as Reported in ...

Tue, 27 Feb 2018 12:00:00 GMT

Pluristem Therapeutics Inc. (PSTI) Catches Eye: Stock Jumps 5.1%

Wed, 11 Oct 2017 11:48:45 GMT

Whirling Stocks: Tanzanian Royalty Exploration Corporation (NYSE:TRX ...

Tue, 24 Apr 2018 15:11:15 GMT

Y/E Jun Revenue (US$m) EBITDA (US$m) PBT (US$m) EPS (c) P/E (x) P/CF (x)
2016A 2.8 (25.5) (20.2) (25.36) N/A N/A
2017A 0.0 (30.2) (24.2) (27.63) N/A N/A
2018E 0.0 (34.9) (28.5) (26.72) N/A N/A
2019E 0.0 (48.2) (45.0) (38.88) N/A N/A

Last updated on 07/03/2018

Investment summary

Pluristem continues to advance its PLX technology platform. In a recent paper it investigated the application of these cells for their ability to inhibit tumor growth; it was found that the cells inhibit growth of a mouse xenograft of a triple-negative breast cancer cell line and induced complete remissions in three out of 10 mice. Additionally, PLX-PAD received approval for an expanded access program from the FDA, allowing it to be used to treat critical limb ischemia (CLI) outside the ongoing Phase III clinical study.

Last updated on 28/02/2018

Industry outlook

Pluristem has been investigating the potential therapeutic benefit of cells derived from the placenta which offers a rich supply of cells of multiple lineages from tissue that would otherwise be medical waste. Although these cells are not stem cells and lack the immortality and pluripotency to meet that definition, they secrete a wide array of cytokines and growth factors and can exert a potent influence on the function of other cells in the body.

Last updated on 02/02/2018

Key management

Zami Aberman, CEO
Yaky Yanay, CFO
Karine Kleinhaus, IR
Esther Lukasiewicz Hagai, VP of Clinical & Medical Affairs
Erez Egozi, VP of Finance

Company address

MATAM Advanced Technology Park
Building #5
Haifa
31905
Israel
View website