Pluristem Therapeutics (PSTI)

Business description

Pluristem is a biotech company, headquartered in Israel, focused on the development of cell-based therapeutics derived from placenta. The company is advancing PLX-PAD for critical limb ischemia (CLI) with a Phase III study on hip fracture. PLX-R18 is being advanced for acute radiation syndrome and hematopoietic cell transplant.

Stock data

Market cap.US$135.6m
Last closeUS$5.22
High / Low (52 weeks)US$1.8 / US$1.1
Stock market listingUS, Tel Aviv Stock Exchange
Forecast net cash (US$m)28.8
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual17.522.6(19.4)
Relative *17.318.6(28.3)

* % Relative to local index

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Company news

Can Pluristem Therapeutics Corner The Acute Radiation Syndrome Market?

Tue, 11 Apr 2017 21:45:00 GMT

Onconova Therapeutics and Pluristem Therapeutics Surge as Candidate Drugs Move ...

Wed, 05 Apr 2017 12:33:45 GMT

Pluristem Therapeutics - A Potential Beneficiary Of The 21st Century Cures Act

Fri, 16 Dec 2016 13:18:45 GMT

Pluristem Signs Term Sheet for $30 Million Equity Investment Agreement with a ...

Tue, 25 Oct 2016 10:41:08 GMT

Executive Shifts at Pluristem Therapeutics

Tue, 18 Apr 2017 13:52:30 GMT

Y/E Jun Revenue (US$m) EBITDA (US$m) PBT (US$m) EPS (c) P/E (x) P/CF (x)
2015A 0.4 (27.3) (24.7) (35.11) N/A N/A
2016A 2.8 (25.5) (23.2) (29.22) N/A N/A
2017E 0.0 (31.5) (29.3) (30.06) N/A N/A
2018E 0.0 (40.9) (41.5) (41.33) N/A N/A

Last updated on 28/03/2017

Investment summary

Pluristem Therapeutics is developing allogenic cell therapies derived from donated placental tissue. The company has two products, PLX-PAD for the treatment of vascular disorders and PLX-R18 for hematologic disorders. The lead program is for critical limb ischemia (CLI), with a Phase III expected to start in 2017. Based on feedback from both the FDA and EMA, a single pivotal 250-patient study will be required for approval.

Last updated on 04/04/2017

Industry outlook

Pluristem has been investigating the potential therapeutic benefit of cells derived from the placenta which offers a rich supply of cells of multiple lineages from tissue that would otherwise be medical waste. Although these cells are not stem cells and lack the immortality and pluripotency to meet that definition, they secrete a wide array of cytokines and growth factors and can exert a potent influence on the function of other cells in the body.

Last updated on 04/04/2017

Key management

Zami Aberman, CEO
Yaky Yanay, CFO
Esther Lukasiewicz Hagai, VP of Clinical & Medical Affairs
Erez Egozi, VP of Finance

Company address

MATAM Advanced Technology Park
Building #5
Haifa
31905
Israel
View website