SymBio Pharmaceuticals (4582)

Business description

SymBio is a Japanese specialty pharma company with a focus on oncology, haematology and pain management. Treakisym was in-licensed from Astellas in 2005. Rigosertib was in-licensed from Onconova and IONSYS was in-licensed from The Medicines Company.

Stock data

Market cap.¥11462.1m
Last close¥234.00
High / Low (52 weeks)¥368.0 / ¥200.0
Stock market listingTYO
Forecast net cash (¥m)2111
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual(7.9)12.5(0.4)
Relative *(7.3)10.3(20)

* % Relative to local index

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Company news

Initiation of Phase 3 Clinical Trial on the Patient-controlled Pain Management ...

Mon, 13 Jun 2016 05:15:00 GMT

Onconova and SymBio Complete License Agreement for Rigosertib, a Phase III ...

Fri, 08 Jul 2011 11:02:12 GMT

Symbio Pharmaceuticals Ltd (4582) Jumped 0.42% on Aug 9

Wed, 09 Aug 2017 05:15:00 GMT

Chinese Pharmaceuticals Market: Trends, Reforms, Opportunities and Revenue ...

Wed, 26 Aug 2015 12:56:15 GMT

Chinese Pharmaceutical Market: Forecasts and Outlooks 2014-2024

Tue, 29 Jul 2014 13:07:30 GMT

Y/E Dec Revenue (¥m) EBITDA (¥m) PBT (¥m) EPS (fd) (¥) P/E (x) P/CF (x)
2015A 1933.0 (2527.0) (2630.0) (81.3) N/A N/A
2016A 2368.0 (2101.0) (2317.0) (59.0) N/A N/A
2017E 2902.0 (3161.0) (3261.0) (69.1) N/A N/A
2018E 3820.0 (2272.0) (2284.0) (47.7) N/A N/A

Last updated on 20/07/2017

Investment summary

SymBio is well on the way to becoming a key speciality pharma partner for Asia-Pacific markets. The company has in-licensing deals for two orphan blood cancer products and a pain management device (IONSYS). Treakisym is approved for r/r low grade NHL/MCL and during 2016 received approvals in CLL and first-line low grade NHL/MCL; these recent approvals could more than double current sales (JPY4.7bn in 2016). Intravenous Rigosertib is in development for myelodysplastic syndromes (MDS) and has started a pivotal Phase III global study; SymBio is enrolling patients in Japan and interim data are expected during H217. SymBio has initiated a Phase I study of high-dose oral rigosertib and intends to participate in a planned global trial in untreated higher-risk MDS patients.

Last updated on 03/08/2017

Industry outlook

SymBio is focused on in-licensing niche opportunities in hard-to-treat indications often overlooked by big pharma. Building its own commercial infrastructure in the future could help establish SymBio more firmly as a partner of choice in Asia-Pacific. An in-house screening process to select additional pipeline candidates for development and commercialisation will be key to driving operating leverage.

Last updated on 03/08/2017

Key management

Fuminori Yoshida, Representative Director, President & CEO
Kazuo Asakawa, Corporate Officer
Tsutomu Abe, Corporate Officer

Company address

Toranomon 30 Mori Building
3-2-2
Toranomon
MINATO-KU, Tokyo
105-0001
Japan
+81-3-54721125
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