Transgene (TNG)

Business description

Transgene is a French company developing immunotherapy agents for cancer and infectious diseases. Oncolytic virus Pexa-Vec (Phase III for HCC) and cancer vaccine TG4010 (Phase II for NSCLC) are the lead clinical candidates.

Stock data

Market cap.€180m
Last close€3.19
High / Low (52 weeks)€3.4 / €2.3
Stock market listingEU
Forecast net debt (€m)29.4
Forecast gearing ratio (%)164
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual22.714.79.0
Relative *16.65.2(6.1)

* % Relative to local index

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Company news

BRIEF-Transgene SA says first results from Phase 2 trial could be expected ...

Mon, 13 Mar 2017 18:22:30 GMT

Transgene Announces Financial Calendar for 2017

Thu, 05 Jan 2017 17:02:24 GMT

Transgene Enters New Phase in Its Strategic Development

Thu, 07 Jan 2016 07:00:35 GMT

Transgene and ABL Announce the Acquisition by ABL Europe of Transgene's ...

Wed, 03 Feb 2016 17:00:33 GMT

Transgene Announces Final Overall Survival Data from Phase 2b TIME Trial with ...

Tue, 08 Sep 2015 17:00:25 GMT

Y/E Dec Revenue (€m) EBITDA (€m) PBT (€m) EPS (c) P/E (x) P/CF (x)
2015A 9.9 (25.7) (28.9) (78.08) N/A N/A
2016A 10.3 (20.1) (22.8) (42.33) N/A N/A
2017E 8.3 (32.0) (35.0) (62.11) N/A N/A
2018E 8.6 (33.6) (36.8) (65.19) N/A N/A

Last updated on 24/03/2017

Investment summary

Transgene is focused on advancing the clinical development of its cancer immunotherapy products (oncolytic virus Pexa-Vec, MUC1 cancer vaccine TG4010) and infectious disease programs (TG1050 for HBV and TG4001 for HPV) in combination with immune checkpoint inhibitors (ICIs). Two combination clinical trials have recently started: TG4010+Opdivo in the 2nd-line treatment of NSCLC and Pexa-Vec+Yervoy in the first-line treatment of liver cancer/other solid tumours. An additional 5 trials will start before YE17. Transgene and partner Sillajen are running a global 600-patient Phase III study in liver cancer. TG1050 for HBV is advancing through Phase I/Ib testing. In October 2016 it announced a collaboration agreement with Merck and Pfizer to evaluate TG4001 with Avelumab in HPV-positive Head & Neck Cancer patients in a Phase I/II Study. Cash and equivalents at end Q316 amounted to €25.4m. In November 2016 the company raised an additional €46.4m (gross) through a rights issue that will fund operations to the end of 2018.

Last updated on 04/04/2017

Industry outlook

Immunotherapies are among the most promising class of products for cancer. Increased attention is now being paid to the use of combination therapy approaches to improve cancer response rates further.

Last updated on 04/04/2017

Key management

Philippe Archinard, Chairman & CEO
Lucie Larguier, Director of IR

Company address

Boulevard Gonthier d’Andernach
Parc d’Innovation - CS80166
Illkirch-Graffensta
F-67405
France
+33 (0)3 88 27 91 00
View website