Transgene (TNG)

Business description

Transgene is a French company developing immunotherapy agents for cancer and infectious diseases. Oncolytic virus Pexa-Vec (Phase III for HCC) and cancer vaccine TG4010 (Phase II for NSCLC) are the lead clinical candidates.

Stock data

Market cap.€189.1m
Last close€3.35
High / Low (52 weeks)€3.6 / €2.5
Stock market listingEU
Forecast net debt (€m)29.4
Forecast gearing ratio (%)164
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual1.51525.015711.0993
Relative *(0.6423)2.1517(6.9748)

* % Relative to local index

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Company news

3.34

Fri, 27 May 2011 20:04:32 GMT

Transgene and ABL Announce the Acquisition by ABL Europe of Transgene's ...

Wed, 03 Feb 2016 17:00:33 GMT

Transgene SA: Agreement with FDA Announced for Special Protocol Assessment for ...

Thu, 16 Apr 2015 16:00:32 GMT

Transgene Enters New Phase in Its Strategic Development

Thu, 07 Jan 2016 07:00:35 GMT

Transgene SA (TNG) Declines -0.9% on Oct 20

Fri, 20 Oct 2017 12:45:00 GMT

Y/E Dec Revenue (€m) EBITDA (€m) PBT (€m) EPS (c) P/E (x) P/CF (x)
2015A 9.9 (25.7) (28.9) (78.08) N/A N/A
2016A 10.3 (20.4) (23.1) (42.90) N/A N/A
2017E 8.3 (32.0) (35.0) (62.11) N/A N/A
2018E 8.6 (33.6) (36.8) (65.19) N/A N/A

Last updated on 02/10/2017

Investment summary

Transgene is focused on the development of its cancer immunotherapy products (oncolytic virus Pexa-Vec, MUC1 cancer vaccine TG4010) and infectious disease programs (TG1050 for HBV and TG4001 for HPV) in combination with immune checkpoint inhibitors (ICIs). Four combination clinical trials have started: a Phase 2 trial testing TG4010+Opdivo in 2nd-line NSCLC, a Phase 1 trial with Pexa-Vec+Yervoy in solid tumours, a Phase 1/2 of Pexa-Vec+metronomic cyclophosphamide in HER2 negative breast cancer and a Phase II with Pexa-Vec+Opdivo in 1st line advanced liver cancer. Transgene and partner Sillajen are running a global 600-patient Phase III study in liver cancer. TG1050 for HBV is advancing through Phase I/Ib testing. It has an agreement with Merck and Pfizer to evaluate TG4001 with Avelumab in HPV+ Head & Neck Cancer patients in a Phase I/II study. Transgene also has a collaboration with BMS to test TG4010 in combination with Opdivo and chemotherapy in 1L NSCLC. Cash at 30 June 2017 was €43.9m, sufficient into end 2018.

Last updated on 03/10/2017

Industry outlook

Immunotherapies are among the most promising class of products for cancer. Increased attention is now being paid to the use of combination therapy approaches to improve cancer response rates further.

Last updated on 03/10/2017

Key management

Philippe Archinard, Chairman & CEO
Lucie Larguier, Director of IR

Company address

Boulevard Gonthier d’Andernach
Parc d’Innovation - CS80166
Illkirch-Graffensta
F-67405
France
+33 (0)3 88 27 91 00
View website