TxCell (TXCL)

Business description

TxCell is developing regulatory T-cell therapies against autoimmune and inflammatory disorders. It is now focused on a novel CAR Treg technology platform. A clinical trial in transplantation may start in 2018. Ovasave for Crohn’s disease is at clinical stage but is on hold.

Stock data

Market cap.€36.1m
Last close€1.86
High / Low (52 weeks)€5.3 / €1.7
Stock market listingEU
Forecast net debt (€m)3.6
Forecast gearing ratio (%)374
SectorPharmaceutical & healthcare

Price performance

Relative *(7.5)(17.4)(69.6)

* % Relative to local index

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Company news

TxCell Re-acquires Full Rights to Its Lead Product Ovasave®

Wed, 02 Dec 2015 16:41:15 GMT

TxCell Secures Key CAR-Treg Patent Through Exclusive Option Agreement with ...

Mon, 02 Nov 2015 16:45:32 GMT

TxCell 2016 Financial Results

Thu, 09 Mar 2017 17:26:15 GMT

TxCell to Hold Conference Call on Friday, March 10, 2017 Following the ...

Tue, 07 Mar 2017 17:01:27 GMT

TxCell raises cash for first-in-man CAR-Treg cell therapy study

Fri, 24 Feb 2017 14:39:46 GMT

Investment summary

TxCell’s novel CAR-modified regulatory T-cell (CAR Treg) platform continues to develop well. TxCell has four indications in preclinical development with the first ever CAR Treg trial, in transplant rejection, anticipated by TxCell to start by late 2018. This could provide powerful clinical proof-of-concept data by 2020. In 2017, an €11.1m gross rights issue provided funding for 2017 added to year end €3.5m cash. A 2017 operational cash use of €13m is guided by management. In 2018, warrants could bring a further €10.8m in cash.

Last updated on 04/04/2017

Y/E Dec Revenue (€m) EBITDA (€m) PBT (€m) EPS (c) P/E (x) P/CF (x)
2014A N/A N/A N/A N/A N/A N/A
2015A 0.9 (10.8) (10.8) (87.7) N/A N/A
2016E 0.0 (11.9) (12.7) (97.6) N/A N/A
2017E 0.0 (11.1) (11.3) (55.5) N/A N/A

Last updated on 22/03/2017

Latest video

Executive Interview - TxCell

Industry outlook

Celgene’s $300m acquisition of Delinia, a preclinical Treg company, gives a benchmark on Treg deals. TxCell is developing two platform technologies: ENTrIA and ASTrIA. ENTrIA uses chimeric antigen receptor (CAR) technology. A granted European patent offers broad protection. CAR Treg development is ongoing in transplant, lupus nephritis, Bullbous pemphigoid (skin) and multiple sclerosis. ASTrIA, is the basis for Ovasave (on hold) for Crohn’s disease.

Last updated on 04/04/2017

Key management

Stéphane Boissel, CEO
Raphael Flipo, CFO

Company address

Les Cardoulines HT1
Allée de la Nertière
Sophia Antipolis
+33(0) 497 218 300
View website