TxCell (TXCL)

Business description

TxCell is developing regulatory T-cell therapies against autoimmune and inflammatory disorders. It is now focused on a novel CAR Treg technology platform. A clinical trial in transplantation may start in 2018. Ovasave for Crohn’s disease is at clinical stage but is on hold.

Stock data

Market cap.€34.8m
Last close€1.72
High / Low (52 weeks)€3.9 / €1.6
Stock market listingEU
Forecast net debt (€m)3.1
Forecast gearing ratio (%)83
SectorPharmaceutical & healthcare

Price performance

Relative *(5.1)(3.5)(54.1)

* % Relative to local index

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Company news

TxCell hires Lentigen to make vectors used to produce its organ rejection cell ...

Tue, 20 Jun 2017 13:33:41 GMT

TxCell: Financial Information for The 2nd Quarter of 2017

Wed, 26 Jul 2017 15:56:15 GMT

TxCell Secures Key CAR-Treg Patent Through Exclusive Option Agreement with ...

Mon, 02 Nov 2015 16:45:32 GMT

TxCell Announces Successful Key Milestone in the Technology Transfer To CMO ...

Thu, 25 Feb 2016 17:30:37 GMT

TxCell 2016 Financial Results

Thu, 09 Mar 2017 17:31:31 GMT

Investment summary

TxCell has agreed an important manufacturing supply contract with Lentigen, a German-US producer of the critical lentivirus reagent essential for modifying T-cells. This is a core element for the development of CAR-modified regulatory T-cells (CAR Treg). Production of any modified T-cell therapy is complex and companies need to be able to scale up production and keep costs and prices under control. In 2018, warrants could bring a further €10.8m in cash covering costs until the IND is filed for the first ever CAR Treg clinical trial.

Last updated on 03/08/2017

Y/E Dec Revenue (€m) EBITDA (€m) PBT (€m) EPS (c) P/E (x) P/CF (x)
2015A 0.9 (10.8) (10.8) (87.7) N/A N/A
2016A 0.0 (11.9) (12.7) (97.6) N/A N/A
2017E 0.0 (11.1) (11.3) (55.5) N/A N/A
2018E 0.0 (11.0) (11.0) (31.4) N/A N/A

Last updated on 14/07/2017

Latest video

Executive Interview - TxCell

Industry outlook

Celgene’s $300m acquisition of Delinia, a preclinical Treg company, gives a benchmark on Treg deals. TxCell is developing two platform technologies: ENTrIA and ASTrIA. ENTrIA uses chimeric antigen receptor (CAR) technology. A granted European patent offers broad protection. CAR Treg development is ongoing in transplant, lupus nephritis, Bullbous pemphigoid (skin) and multiple sclerosis. A collaboration with INSERM on MS and transplant was announced in May.

Last updated on 03/08/2017

Key management

Stéphane Boissel, CEO
Raphael Flipo, CFO

Company address

Les Cardoulines HT1
Allée de la Nertière
Sophia Antipolis
+33(0) 497 218 300
View website