Viralytics (VLA)

Business description

Viralytics is a biopharmaceutical company developing Cavatak oncolytic virotherapy to target late-stage melanoma and other solid tumour types. It is trialling Cavatak as a monotherapy and in combination with checkpoint inhibitors.

Stock data

Market cap.A$175.3m
Last closeA$0.63
High / Low (52 weeks)A$1.3 / A$0.6
Stock market listingAU, US
Forecast net cash (A$m)23.3
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual(9.4)(16)(37)
Relative *(8.2)(16.1)(39)

* % Relative to local index

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Company news

Viralytics bags $4M to advance cancer treatment

Mon, 25 Jan 2016 04:56:01 GMT

Viralytics attracts funding support from Chinese life sciences company

Sun, 07 Jan 2018 22:07:30 GMT

Viralytics Ltd ADR (VRACY) Money Flow Index Nearing Key Level

Tue, 20 Feb 2018 00:00:00 GMT

Viralytics Ltd reports positive results of melanoma cancer fighting combination

Tue, 19 Apr 2016 05:49:18 GMT

Viralytics Ltd reveals positive cancer immunotherapy results

Mon, 14 Nov 2016 00:28:43 GMT

Y/E Jun Revenue (A$m) EBITDA (A$m) PBT (A$m) EPS (fd) (c) P/E (x) P/CF (x)
2016A 4.7 (8.5) (8.0) (3.8) N/A N/A
2017A 6.5 (11.7) (11.3) (4.7) N/A N/A
2018E 5.9 (12.4) (12.0) (5.0) N/A N/A
2019E 6.1 (12.6) (12.5) (5.2) N/A N/A

Last updated on 13/12/2017

Investment summary

Viralytics presented updates at SITC in November highlighting further promising clinical trial data for its Cavatak oncolytic virus immunotherapy. The CAPRA trial of intra-lesional (IL) Cavatak + Keytruda in melanoma reported a 61% response rate in the first 23 of 50 patients. In the MITCI study of IL Cavatak + Yervoy the response rate to date is 57% (8/14) in checkpoint inhibitor naïve patients and 29% (2/7) in patients who had failed single line anti-PD1 therapies - the study is now focused on patients who failed prior single line anti-PD1 therapy. Among 19 evaluable patients in the Keynote 200 trial of IV Cavatak + Keytruda, responses were observed in 3/6 advanced lung cancer and 5/13 bladder cancer patients. Viralytics plans to add 4 new combo studies in the next 6 months in head and neck cancer, melanoma, metastatic uveal melanoma and colorectal cancer. Cash at 30 September was A$28m.

Last updated on 02/02/2018

Industry outlook

The FDA approval of Amgen's Imlygic has made oncolytic virotherapy a commercial reality. The December 2016 licence deal between Bristol-Myers Squibb and PsiOxus for its preclinical oncolytic virus NG-348 highlights the potential value of oncolytic virotherapy products; terms included US$50m upfront and up to US$886m in milestones.

Last updated on 02/02/2018

Key management

Paul Hopper, Chairman
Malcolm McColl, CEO
Robert Vickery, CFO
Professor Darren Shafren , CSO

Company address

Suite 305
Level 3
66 Hunter Street
Sydney
NSW 2000
Australia
+61 (0)2 9988 4000
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