Viralytics (VLA)

Business description

Viralytics is a biopharmaceutical company developing Cavatak oncolytic virotherapy to target late-stage melanoma and other solid tumour types. It is trialling Cavatak as a monotherapy and in combination with checkpoint inhibitors.

Stock data

Market cap.A$149.4m
Last closeA$0.62
High / Low (52 weeks)A$1.3 / A$0.6
Stock market listingAU, US
Forecast net cash (A$m)23.3
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual(23.9)(31.1)(50.8)
Relative *(23.8)(34.9)(54.7)

* % Relative to local index

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Company news

Viralytics bags $4M to advance cancer treatment

Mon, 25 Jan 2016 04:56:01 GMT

Viralytics Ltd reports positive results of melanoma cancer fighting combination

Tue, 19 Apr 2016 05:49:18 GMT

Viralytics Ltd reveals positive cancer immunotherapy results

Mon, 14 Nov 2016 00:28:43 GMT

Why Viralytics Ltd Climbed 5% Today

Tue, 11 Apr 2017 05:01:38 GMT

Viralytics Reports Positive Final Results From CAVATAK Phase 2 Melanoma Trial

Wed, 03 Jun 2015 09:33:37 GMT

Y/E Jun Revenue (A$m) EBITDA (A$m) PBT (A$m) EPS (fd) (c) P/E (x) P/CF (x)
2016A 4.7 (8.5) (8.0) (3.8) N/A N/A
2017A 6.5 (11.7) (11.3) (4.7) N/A N/A
2018E 5.9 (12.4) (12.0) (5.0) N/A N/A
2019E 6.1 (12.6) (12.5) (5.2) N/A N/A

Last updated on 05/12/2017

Investment summary

Viralytics continues to report impressive preliminary data for Cavatak in combination with immune checkpoint inhibitors (ICIs), whether administered intravenously (iv) or by intra-tumoural injection. Viralytics is currently recruiting additional patients in expansion cohorts in melanoma, lung and bladder cancers in order to obtain more robust estimates of tumour response rates. It has announced plans to initiate four Phase I studies in additional indications and has commenced planning for a potential pivotal study of Cavatak plus Yervoy in melanoma patients who had failed prior single-agent, anti-PD1 ICI therapy, a serious unmet medical need. Updates on MITCI, CAPRA and Keynote 200 are expected in Q218. We increase our valuation to A$469m or A$1.95/share (vs A$408m and A$1.70/share).

Last updated on 05/12/2017

Industry outlook

The FDA approval of Amgen's Imlygic has made oncolytic virotherapy a commercial reality. The December 2016 licence deal between Bristol-Myers Squibb and PsiOxus for its preclinical oncolytic virus NG-348 highlights the potential value of oncolytic virotherapy products; terms included US$50m upfront and up to US$886m in milestones.

Last updated on 02/11/2017

Key management

Paul Hopper, Chairman
Malcolm McColl, CEO
Robert Vickery, CFO
Professor Darren Shafren , CSO

Company address

Suite 305
Level 3
66 Hunter Street
Sydney
NSW 2000
Australia
+61 (0)2 9988 4000
View website