Viralytics (VLA)

Business description

Viralytics is a biopharmaceutical company developing Cavatak oncolytic virotherapy to target late-stage melanoma and other solid tumour types. It is trialling Cavatak as a monotherapy and in combination with checkpoint inhibitors.

Stock data

Market cap.A$204.5m
Last closeA$0.85
High / Low (52 weeks)A$1.3 / A$0.8
Stock market listingAU, US
Forecast net cash (A$m)34.9
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual(12.8)(20.6)(6.6)
Relative *(13.2)(19.9)(9.9)

* % Relative to local index

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Company news

Viralytics Ltd reports positive results of melanoma cancer fighting combination

Tue, 19 Apr 2016 05:49:18 GMT

Is The Needle Ready to Move For Viralytics Ltd (VLA.AX) Shares?

Wed, 16 Aug 2017 07:30:00 GMT

Why Viralytics Ltd Climbed 5% Today

Tue, 11 Apr 2017 05:01:38 GMT

Viralytics and Merck & Co., Inc., Kenilworth, New Jersey, USA to Collaborate ...

Fri, 06 Nov 2015 11:03:42 GMT

Viralytics Reports Positive Final Results From CAVATAK Phase 2 Melanoma Trial

Wed, 03 Jun 2015 09:33:37 GMT

Y/E Jun Revenue (A$m) EBITDA (A$m) PBT (A$m) EPS (fd) (c) P/E (x) P/CF (x)
2015A 2.5 (6.0) (5.5) (3.0) N/A N/A
2016A 4.7 (8.5) (8.0) (3.8) N/A N/A
2017E 4.3 (12.2) (11.7) (4.9) N/A N/A
2018E 4.8 (11.7) (11.4) (4.7) N/A N/A

Last updated on 14/07/2017

Investment summary

Viralytics presented data at the American Association for Cancer Research (AACR) in April showing a 50% response rate (11/22) in patients with advanced melanoma treated with its Cavatak virotherapy in combination with Yervoy in the Phase Ib MITCI trial. An update at ASCO showed a 23% response rate (3/13) in the subset of patients who had failed PD1/L1 checkpoint inhibitor therapy; the trial has been expanded to recruit an extra 44 patients who had failed prior PD1/L1 therapy. The CAPRA trial of Cavatak plus Keytruda has been expanded to enrol up to 50 late-stage melanoma patients following a 60% response rate in the first 15 patients. Other ongoing trials include the Phase I/II CANON trial in superficial bladder cancer; and Keynote 200 (STORM Part B), a Phase Ib trial of IV Cavatak and Keytruda in advanced lung and bladder cancer. Cash at 31 March was A$39m.

Last updated on 03/08/2017

Industry outlook

The FDA approval of Amgen's Imlygic has made oncolytic virotherapy a commercial reality. The December 2016 licence deal between Bristol-Myers Squibb and PsiOxus for its preclinical oncolytic virus NG-348 highlights the potential value of oncolytic virotherapy products; terms included US$50m upfront and up to US$886m in milestones.

Last updated on 03/08/2017

Key management

Paul Hopper, Chairman
Malcolm McColl, CEO
Robert Vickery, CFO
Professor Darren Shafren , CSO

Company address

Suite 305
Level 3
66 Hunter Street
Sydney
NSW 2000
Australia
+61 (0)2 9988 4000
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