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Celyad (CYAD)

Business description

Celyad is developing an innovative Natural Killer Receptor CAR T-cvell therapy (CYAD-01). This focusses on AML and metastatic coloretal cancer. A comprehensive set of clinical studies is beeing initiated.

Stock data

Market cap.€291m
Last close€25.26
High / Low (52 weeks)€54.0 / €22.9
Stock market listingEU
Forecast net cash (€m)45.9
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual(1.3)(3.7)(32.8)
Relative *(0.4)(1.6)(29.6)

* % Relative to local index

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Company news

Y/E Dec Revenue (€m) EBITDA (€m) PBT (€m) EPS (c) P/E (x) P/CF (x)
2016A 8.5 (21.2) (20.0) (209.0) N/A N/A
2017A 3.5 (22.3) (26.8) (279.0) N/A N/A
2018E 0.0 (26.5) (27.3) (243.0) N/A N/A
2019E 0.0 (27.8) (28.5) (238.0) N/A N/A

Last updated on 02/08/2018

Investment summary

The FDA’s sign off on Celyad’s first clinical trial design for its allogeneic NRK CAR T-cell therapy (CYAD-101) is an important milestone. The study, possibly staring in Q4 2018, mirrors the current colorectal SHRINK trial a combination of autologous CYAD-01 therapy with FOLFOX chemotherapy. This gives Celyad the lead in a mass-market solid cancer where allogeneic therapy is likely to be essential. The indicative value has been increased to €1,090m (€89 per share) from €1,040m (€84 per share) pending further data.

Last updated on 02/08/2018

Industry outlook

The CART therapeutic area remains a hot area for investment with increasing interest in the next stage of allogeneic products, an area where Celyad holds a key patent with a Novartis deal. Celyad remains in a key position in both AML and mCRC with initial moves into combination solid tumour therapies.

Last updated on 27/07/2018

Key management

Michel Lussier, Chairman
Dr Christian Homsy, CEO
Patrick Jeanmart, CFO
Dr Gaƫtane Metz, COO

Company address

Rue Edouard Belin 12
1435 Mont-Saint-Guibert
Belgium
+32(0)10 39 41 00
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