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Immutep (IMM)

Business description

Immutep has a pipeline of four LAG-3 related product candidates: eftilagimod alpha (IMP321) for cancer chemo-immunotherapy and immunotherapy-immunotherapy combinations, two partnered products IMP731 (GSK) and IMP701 (Novartis), as well as IMP761 for autoimmune diseases.

Stock data

Market cap.A$102m
Last closeA$0.03
High / Low (52 weeks)A$84.5 / A$35.5
Stock market listingAU
Forecast net cash (A$m)10
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceuticals & healthcare

Price performance

%1m3m12m
Actual(3.2)(18.9)36.4
Relative *(7.6)(23.2)33.3

* % Relative to local index

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Company news

Prima BioMed Changes Its Name to Immutep Ltd

Mon, 20 Nov 2017 06:56:15 GMT

BRIEF-Immutep Ltd Enters Into Clinical Trial Collaboration With Merck & Co

Mon, 12 Mar 2018 01:18:45 GMT

Immutep to Present Interim Results from TACTI-mel Clinical Trial in Global Webcast

Thu, 17 May 2018 12:00:00 GMT

Immutep Limited Announces Milestone Payment From Chinese Partner EOC Pharma

Thu, 01 Feb 2018 03:00:00 GMT

Prima BioMed Becomes Immutep

Tue, 28 Nov 2017 00:11:15 GMT

Y/E Jun Revenue (A$m) EBITDA (A$m) PBT (A$m) EPS (c) P/E (x) P/CF (x)
2017A 4.1 (7.8) (8.4) (0.4) N/A N/A
2018A 6.9 (11.4) (10.9) (0.5) N/A N/A
2019E 10.9 (7.6) (6.9) (0.2) N/A N/A
2020E 2.8 (15.3) (14.9) (0.5) N/A N/A

Last updated on 18/12/2018

Investment summary

Immutep has three promising candidates in clinical trials and one preclinical asset, all based on Lymphocyte activation gene-3, LAG-3 (one partnered with GSK and a second partnered with Novartis). Lead in-house LAG-3 product, eftilagimod alpha (efti), is being developed in metastatic breast cancer combined with chemo (155 of 226 patients recruited in randomised Phase IIb, initial PFS data expected H219) and in melanoma in combination with Keytruda (61% exploratory response rate from start of Keytruda monotherapy screening in three dose-finding cohorts, 3/6 (50%) responders in an additional cohort). Novartis and GSK are progressing clinical trials of partnered LAG-3 programmes: GSK has announced ulcerative colitis as lead indication; Novartis has commenced three Phase II studies with LAG525 this year. Immutep will collaborate with Merck & Co (MSD) in a study of efti plus Keytruda in lung and head and neck cancers in Q119. A trial of efti plus Bavencio in collaboration with Merck KGaA/Pfizer is planned for Q119.

Last updated on 01/02/2019

Industry outlook

Immunotherapies are among the most promising class of products for cancer and autoimmune diseases. The LAG-3 products are potentially first-in-class, each with distinct mechanisms and applications.

Last updated on 01/02/2019

Key management

Marc Voigt , CEO
Jay Campbell, Senior Director, Business Development

Company address

Level 12, 95 Pitt Street
Sydney
NSW
2000
Australia
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