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Angle (AGL)

Business description

Angle is a world leading liquid biopsy company with a potentially disruptive platform technology. The patented Parsortix cell separation platform can harvest circulating tumour cells and other very rare cells from a blood sample for downstream analysis.

Stock data

Market cap.£76.1m
Last close53.00p
High / Low (52 weeks)74.0p / 38.0p
Stock market listingLN
Forecast net debt (m)N/A
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceuticals & healthcare

Price performance

%1m3m12m
Actual0.023.38.7
Relative *(3.2)19.910.4

* % Relative to local index

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Company news

ANGLE appoints leading prostate cancer surgeon Greg Shaw as scientific advisor

Mon, 14 May 2018 06:38:41 GMT

ANGLE PLC opens up potential route to market for Parsortix platform

Tue, 06 Feb 2018 13:00:08 GMT

ANGLE PLC's Andrew Newland on 'breakthrough in culturing CTCs'

Thu, 19 Apr 2018 11:48:45 GMT

ANGLE upbeat on QIAGEN collaboration ahead of poster presentation

Thu, 03 May 2018 07:02:23 GMT

Leading professor to host webinar on ANGLE's Parsortix system

Tue, 16 Jan 2018 08:13:56 GMT

Investment summary

Angle's Parsortix cell separation platform is used to detect and harvest circulating tumour cells from blood. CTCs provide the complete picture since viable, intact CTCs can be used for DNA, RNA and protein analysis as well as culturing and xenograft models. Angle acquired Ziplex platform of Axela, a multiplex solution providing enhanced analysis of protein, DNA and RNA. This will allow Angle to offer a "sample to answer" product to its clients. A key catalyst in the near term is the completion of the FDA clinical studies in breast cancer expected in H218 and a potential subsequent submission to the FDA. The company reported results from its two studies (n=200 each) for triaging women with ovarian masses before surgery. Reported ROC-AUC was high at 95.1% (assay combines the expression levels of 9 different genes and 4 serum markers). Angle has existing collaboration agreements with three multinationals (Qiagen, Philips and Abbott) indicating growing interest in CTCs from large players. We are updating our estimates.

Last updated on 01/02/2019

Y/E Apr Revenue (£m) EBITDA (£m) PBT (£m) EPS (p) P/E (x) P/CF (x)
2016A 0.4 (4.9) (5.0) (7.97) N/A N/A
2017A 0.5 (6.7) (6.9) (8.03) N/A N/A
2018E N/A N/A N/A N/A N/A N/A
2019E N/A N/A N/A N/A N/A N/A

Last updated on 18/01/2019

Latest video

Angle plc

Industry outlook

The precision medicine approach is an initiative aiming to improve treatment efficacy by tailoring the treatment to the patient and their disease with liquid biopsy being one of the key enabling tools.

Last updated on 01/02/2019

Key management

Andrew Newland, CEO
Ian Griffiths, FD

Company address

3 Frederick Sanger Road
The Surrey Research Park
Guildford
Surrey
GU2 7YD
United Kingdom
+44 (0)1483 685830
View website