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Atossa Genetics (ATOS)

Business description

Based in Seattle, WA, Atossa Genetics is focused on the development of locally administered pharmaceuticals for the treatment of pre-cancer and early-stage breast cancer. Lead candidate afimoxigene topical gel is expected to start a Phase II study in 2016 in breast hyperplasia or DCIS.

Stock data

Market cap.US$6.9m
Last closeUS$1.22
High / Low (52 weeks)US$10.0 / US$1.2
Stock market listingUS
Forecast net cash (US$m)7.2
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual(24.2)(47.2)(69.9)
Relative *(22.2)(45.2)(71.5)

* % Relative to local index

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Company news

Y/E Dec Revenue (US$m) EBITDA (US$m) PBT (US$m) EPS (c) P/E (x) P/CF (x)
2016A 0.0 (6.9) (7.3) (2951.72) N/A N/A
2017A 0.0 (7.1) (7.2) (1000.81) N/A N/A
2018E 0.0 (11.4) (11.4) (429.43) N/A N/A
2019E 0.0 (7.0) (7.0) (257.02) N/A N/A

Last updated on 12/10/2018

Investment summary

Atossa is advancing endoxifen, a metabolite of tamoxifen, as a topical treatment for high mammographic breast density (MBD), a condition associated with higher cancer risk. Atossa is also developing oral endoxifen as a potential treatment for breast cancer patients refractory to tamoxifen. About 20-25% of the 1.0m women taking tamoxifen worldwide develop resistance to it, and have an increased risk for cancer recurrence. The firm reported positive Phase I data for both formulations, including results showing that patients obtain "steady state" serum endoxifen levels after about 7 days of daily oral dosing.

Last updated on 12/11/2018

Industry outlook

Atossa started Phase II trials for oral and topical endoxifen, and recently completed enrollment for the topical study. The firm also reported positive Phase I topical endoxifen safety data in men and is planning to start a Phase II study in men with gynecomastia. It also started preclinical studies with its IDMC to explore potential use in immunotherapy. Atossa raised $13.4m gross ($12.1m net) through a Q218 rights offering. It reported $15.2m net cash on 30 June 2018, which we believe can sustain operations until early 2020.

Last updated on 12/11/2018

Key management

Steven Quay , CEO
Kyle Guse, CFO

Company address

2300 Eastlake Ave E
Suite 200
Seattle
WA 98102
United States
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