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Cantargia (CANT)

Business description

Cantargia is a clinical stage biotechnology company based in Sweden, established in 2009 and listed on Nasdaq Stockholm main market. It is developing two antibodies against IL1RAP, nidanilimab (CAN04) and CANxx. Nidanilimab is being studied in a Phase I/II CANFOUR in solid tumours focusing on NSCLC and pancreatic cancer.

Stock data

Market cap.SEK1111.9m
Last closeSEK16.80
High / Low (52 weeks)SEK23.3 / SEK6.4
Stock market listingOMX
Forecast net cash (SEKm)61.5
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceutical & healthcare

Price performance

%1m3m12m
Actual(0.3)(11.8)140.0
Relative *1.2(3.9)153.6

* % Relative to local index

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Y/E Dec Revenue (SEKm) EBITDA (SEKm) PBT (SEKm) EPS (fd) (öre) P/E (x) P/CF (x)
2016A 0.0 (47.6) (47.5) (271.96) N/A N/A
2017A 0.0 (60.0) (60.3) (186.00) N/A N/A
2018E 0.0 (85.8) (83.3) (147.34) N/A N/A
2019E 0.0 (93.8) (93.5) (141.19) N/A N/A

Last updated on 22/11/2018

Investment summary

Cantargia is developing two antibodies against IL1RAP: Nidanilimab (CAN04) and CANxx. Nidanilimab is currently being studied in a Phase I/II CANFOUR trial where the Phase I part is focusing on several solid tumours, and the Phase II part will focus on NSCLC and pancreatic cancer. Nidanilimab was well tolerated in the first 16 patients, and final safety data are expected in Q418. Nidanilimab has a dual mechanism of action: inhibition of IL-1 signaling and antibody-dependent cellular cytotoxicity (ADCC). Novartis is starting three Phase III trials in NSCLC with canakinumab (IL-1beta antibody) following some unexpected results from its six-year Phase III cardiovascular outcomes study in heart attack patients. Cantargia has recently up-listed to the Nasdaq Stockholm main market.

Last updated on 29/11/2018

Industry outlook

Increasing the understanding of inflammation in malignant process now includes findings that cytokines are not only produced by the immune cells, but also cancer itself could produce certain cytokines and the associated receptors to escape from the immune response. Therefore, cytokines represent potentially promising class of targets in cancer management.

Last updated on 29/11/2018

Key management

Goran Forsberg, CEO

Company address

81 Medicon Village
Scheelevagen 2, Lund
SE-223
Sweden
+46 46 27 56 260
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