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Medigene (MDG1)

Business description

Medigene is a German biotech company with a core business in cancer immunotherapy. A T cell receptor (TCR) candidate has recently entered the clinic and a dendritic cell (DC) vaccine Phase I/II clinical study is ongoing in Phase II.

Stock data

Market cap.€215.1m
Last close€8.76
High / Low (52 weeks)€18.8 / €7.3
Stock market listingDE
Forecast net cash (€m)68.1
Forecast gearing ratio (%)N/A
TeamHealthcare
SectorPharmaceuticals & healthcare

Price performance

%1m3m12m
Actual(2.7)(8.6)(48.1)
Relative *(3.5)(8.3)(42.8)

* % Relative to local index

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Company news

MediGene AG 2017 Q4 - Results - Earnings Call Slides

Mon, 26 Mar 2018 18:33:24 GMT

BRIEF-Medigene AG Medigene Appoints Dr. Kai Pinkernell To Executive Management ...

Wed, 11 Apr 2018 05:48:45 GMT

Medigene AG to be included in TecDAX Index

Tue, 06 Dec 2016 10:18:45 GMT

bluebird bio expands US$1bn deal with MediGene

Tue, 15 May 2018 05:26:15 GMT

Medigene Collaborates with RXi Pharmaceuticals to Further Sharpen its ...

Mon, 11 Dec 2017 12:00:00 GMT

Y/E Dec Revenue (€m) EBITDA (€m) PBT (€m) EPS (c) P/E (x) P/CF (x)
2016A 9.7 (12.4) (13.4) (66.20) N/A N/A
2017A 11.4 (12.1) (12.4) (60.42) N/A N/A
2018E 10.4 (16.7) (16.3) (70.03) N/A N/A
2019E 11.0 (17.9) (17.1) (70.01) N/A N/A

Last updated on 04/01/2019

Investment summary

Medigene is focused on the rapid development of its cancer immunotherapy technology platforms: dendritic cell (DC) cancer vaccines, adoptive T-cell therapy (TCR) and T-cell specific antibodies (TAB). A Phase II study is ongoing with DC vaccines for acute myeloid leukaemia. For TCRs, Medigene has initiated its first company-led trial with MDG1011 in patients with PRAME expressing AML, MDS or MM. Medigene has announced an exclusive licence agreement with Leiden University to develop TCRs against HA-1 antigen. Its partnership with bluebird bio to utilise its TCR technology platform was recently expanded (US$8m one time payment, US$1m achieved milestone payment, US$250 milestones per target, tiered royalties) to now include six therapeutic candidates. Medigene is well-funded to execute its clinical programme, as of 30 September net cash (including time deposits) was €76.3m.

Last updated on 01/02/2019

Industry outlook

Cancer immunotherapy is attracting huge biotech investor interest. Medigene's DC vaccine technology is a new generation, with multiple potential efficacy and manufacturing benefits over the forerunners, eg Provenge. The TCR programme has similarities to CAR-T products, but with potentially significant efficacy and safety advantages.

Last updated on 01/02/2019

Key management

Prof. Horst Domdey, Chairman
Prof. Dr. Dolores Schendel, CEO
Prof. Dr. Dolores Schendel, CEO

Company address

Lochhamer Str. 11
Martinsried
82152
Germany
+49-89-20 00 33 - 0
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